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Prog. Theor. Phys. Supplement No. 184 (2010) pp. 351-363
Cell Model Approach to Membrane Mediated Protein Interactions
Martin Michael Müller1 and
Markus Deserno2
1Laboratoire de Physique Moléculaire et des Collisions,
ICPMB-FR CNRS 2843,
Université Paul Verlaine-Metz; 1,
boulevard Arago, 57070 Metz, France
2Dept. of Physics, Carnegie Mellon, 5000 Forbes Ave, Pittsburgh,
PA 15213, USA
Abstract:
Membrane-deforming proteins can interact through the curvature
fields they create. In the case of many such proteins a cell model
approach can be used to calculate the energy per protein and
predict, whether it would lead to phase segregation or
bud-formation. Using covariant differential geometry exact results
are derived for the lateral pressure in terms of geometric
properties at the cell boundary. Numerical solutions of the exact
shape equations in the highly nonlinear regime are found and it is
seen that both phase segregation and bud formation can occur.
URL :
http://ptp.ipap.jp/link?PTPS/184/351/
DOI : 10.1143/PTPS.184.351
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